Cdc42 and RhoA reveal different spatio-temporal dynamics upon local stimulation with Semaphorin-3A
نویسندگان
چکیده
منابع مشابه
Cdc42 and RhoA reveal different spatio-temporal dynamics upon local stimulation with Semaphorin-3A
Small RhoGTPases, such as Cdc42 and RhoA, are key players in integrating external cues and intracellular signaling pathways that regulate growth cone (GC) motility. Indeed, Cdc42 is involved in actin polymerization and filopodia formation, whereas RhoA induces GC collapse and neurite retraction through actomyosin contraction. In this study we employed Förster Resonance Energy Transfer (FRET) mi...
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ژورنال
عنوان ژورنال: Frontiers in Cellular Neuroscience
سال: 2015
ISSN: 1662-5102
DOI: 10.3389/fncel.2015.00333